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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1064784Generated: October 30, 2026

2-[5-(4-cyanophenyl)-1-benzofuran-2-yl]ethyl Methanesulfonate → 4-(2-{2-[(2S)-2-methylpyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrile

https://huagongshe.com/reaction/1064784

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[5-(4-cyanophenyl)-1-benzofuran-2-yl]ethyl MethanesulfonateHCID 11393678—
Reactant(S)-2-methylpyrrolidine hydrobromideHCID 20779371—
Product4-(2-{2-[(2S)-2-methylpyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrileHCID 11255988—

Reaction Steps

(2S)-2-Methylpyrrolidine hydrobromide and the product from Example 1C can be processed as described in Example 1D to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06969730B2
Source datasetuspto-grants-2005_11
ORD IDord-b68a829a6bf2457c8b61ee7a4c2c73b8
Source noteuspto-grants-2005_11