Potassium ethylxanthate → HCID 178504598, compound

Participants

Reaction Steps

To a solution of this aminophenol. (233 mg, 1.36 mmol) in ethanol (10 ml) was added potassium O-ethyl dithiocarbonate (300 mg, 1.87 mmol) and the mixture was stirred under heating to reflux for 9 hours. The reaction solution was acidified to pH, 4 with 1 N hydrochloric acid and extracted with chloroform. The organic layer was washed with a saturated sodium chloride solution, dried over anhydrous sodium sulfate and concentraed in vacuo. The resulting residue was purified by a silica gel preparative thin layer chromatography (developing solvent; chloroform:methanol=10:1) and recrystallized from chloroform-ether to provide 223 mg (yield 77%) of 2-mercapto-7-methansulfinylbenzoxazole as pale brown powdery crystals.

Provenance & Evidence