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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1064913Generated: October 25, 2026

(2S)-3-(4-benzyloxy-2-ethyl-phenyl)-2-ethoxy-propionic acid methyl ester → (2S)-2-ethoxy-3-(2-ethyl-4-hydroxy-phenyl)-propionic acid methyl ester

https://huagongshe.com/reaction/1064913

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-3-(4-benzyloxy-2-ethyl-phenyl)-2-ethoxy-propionic acid methyl esterHCID 68615927—
CatalystPalladiumHCID 23938—
Product(2S)-2-ethoxy-3-(2-ethyl-4-hydroxy-phenyl)-propionic acid methyl esterHCID 68617384—

Reaction Steps

In analogy to the procedure described in example 1 d], (2S)-3-(4-benzyloxy-2-ethyl-phenyl)-2-ethoxy-propionic acid methyl ester was hydrogenated over 10% palladium on charcoal to give (2S)-2-ethoxy-3-(2-ethyl-4-hydroxy-phenyl)-propionic acid methyl ester as colorless liquid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06969725B2
Source datasetuspto-grants-2005_11
ORD IDord-23daa797fdd64a1e8a19f2765915aeab
Source noteuspto-grants-2005_11