HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 69280466, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 4-(Chloromethyl)-2-(4-isopropoxyphenyl)-5-methyl-1,3-oxazole | HCID 21974254 | — |
| Reactant | (2S)-2-ethoxy-3-(2-ethyl-4-hydroxy-phenyl)-propionic acid methyl ester | HCID 68617384 | — |
| Product | HCID 69280466 | HCID 69280466 | — |
Reaction Steps
In analogy to the procedure described in example 1 f], (2S)-2-ethoxy-3-(2-ethyl-4-hydroxy-phenyl)-propionic acid methyl ester (example 8 g]) was reacted with 4-chloromethyl-2-(4-isopropoxy-phenyl)-5-methyl-oxazole (example 2 b]) in the presence of cesium carbonate and potassium iodide to yield (S)-2-ethoxy-3-{2-ethyl-4-[2-(4-isopropoxy-phenyl)-5-methyl-oxazol-4-ylmethoxy]-phenyl}-propionic acid methyl ester as colorless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06969725B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-62f32acc655d44da9e4076537c0991f7 |
| Source note | uspto-grants-2005_11 |