HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 4-(Benzyloxy)-1-bromo-2-fluorobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 1-(Benzyloxy)-3-fluorobenzene | HCID 11629801 | — |
| Product | 4-(Benzyloxy)-1-bromo-2-fluorobenzene | HCID 22273933 | — |
Reaction Steps
In analogy to the procedure described in example 8 b], 1-fluoro-3-(phenylmethoxy)-benzene (for the preparation of 1-fluoro-3-(phenylmethoxy)-benzene see: A. A. Durrani, J. H. P. Tyman, J. Chem. Soc., Perkin Trans. 1 1979, 8, 2079-2087) was treated with N-bromosuccinimide in the presence of concentrated sulfuric acid to give 1-bromo-2-fluoro-4-(phenylmethoxy)-benzene as colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06969725B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-8bd00730a5fb494a8abc8748a52453f7 |
| Source note | uspto-grants-2005_11 |