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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1064954Generated: November 3, 2026

Lithium Hydroxide → (S)-2-ethoxy-3-[4-(5-methyl-2-phenyl-oxazol-4-ylmethoxy)-2-trifluoromethyl-phenyl]-propionic acid

https://huagongshe.com/reaction/1064954

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant(S)-2-ethoxy-3-[4-(5-methyl-2-phenyl-oxazol-4-ylmethoxy)-2-trifluoromethyl-phenyl]-propionic acid methyl esterHCID 69279917—
Product(S)-2-ethoxy-3-[4-(5-methyl-2-phenyl-oxazol-4-ylmethoxy)-2-trifluoromethyl-phenyl]-propionic acidHCID 10321472—

Reaction Steps

In analogy to the procedure described in example 1 g], (S)-2-ethoxy-3-[4-(5-methyl-2-phenyl-oxazol-4-ylmethoxy)-2-trifluoromethyl-phenyl]-propionic acid methyl ester was treated with LiOH to obtain (S)-2-ethoxy-3-[4-(5-methyl-2-phenyl-oxazol-4-ylmethoxy)-2-trifluoromethyl-phenyl]-propionic acid as colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06969725B2
Source datasetuspto-grants-2005_11
ORD IDord-8747927596344b868c0e4d3455fd6b17
Source noteuspto-grants-2005_11