HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl ethoxyacetate → [Rac]-3-(4-benzyloxy-2-isopropoxy-phenyl)-2-ethoxy-3-hydroxy-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl ethoxyacetate | HCID 69955 | — |
| Reactant | 4-(Benzyloxy)-2-isopropoxybenzaldehyde | HCID 10635744 | — |
| Product | [Rac]-3-(4-benzyloxy-2-isopropoxy-phenyl)-2-ethoxy-3-hydroxy-propionic acid ethyl ester | HCID 69280524 | — |
Reaction Steps
In analogy to the procedure described in example 47 a], 4-benzyloxy-2-isopropoxy-benzaldehyde [Chemical & Pharmaceutical Bulletin (1998), 46(2), 222-230] was reacted with the enolate of ethyl ethoxyacetate, to yield [rac]-3-(4-benzyloxy-2-isopropoxy-phenyl)-2-ethoxy-3-hydroxy-propionic acid ethyl ester as a mixture of diastereomers in form of a light yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06969725B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-d396664e2eb349128c333e5d9199fdd7 |
| Source note | uspto-grants-2005_11 |