Water → HCID 178441961, compound

HRID 1065105Notes

Reaction equation

HRID 1065105 reaction equation
[C:1]([C:7]#N)(=O)[C:2]([CH3:5])([CH3:4])[CH3:3].[NH2:9][NH:10][C:11]([NH:13][NH2:14])=[S:12].[OH2:15]>>[NH2:9][N:10]1[C:7](=[O:15])[C:1]([C:2]([CH3:5])([CH3:4])[CH3:3])=[N:14][N:13]=[C:11]1[SH:12]

Participants

4

Reactant 3

HCID 962WaterHCID 945273,3-Dimethyl-2-oxobutanenitrileHCID 2724189Thiocarbohydrazide

Product 1

HCID 178441961HCID 178441961, compoundYield 90.1%

Procedure

The procedure followed was as described in Example 1 A, but the reaction mixture of concentrated sulphuric acid, acetic anhydride and pivaloyl cyanide was introduced into an aqueous suspension of 26.6 g (0.25 mol) of thiocarbohydrazide and 300 ml of water. 45.1 g (90.1% of theory) of 4-amino-6-tert.-butyl-3-mercapto-1,2,4-triazin-5(4H)-one (V) of melting point 212°-214° C. were obtained; content, according to the gas chromatogram, >99%.

Sources & evidence

ORD record
ord-a85eea6ac0f540de93ff6305fc98c6e4
Source dataset
uspto-grants-1982_05
Patent number
US04328340

Reaction notes

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