HCID 20541499, compound → HCID 20541497, compound

Participants

Reaction Steps

22 mg of 1,2,3,4,4a,5,6,8a-octahydro-2-oxo-4a-hydroxy-5,5,8a-trimethyl-1,6-methanonaphthalene in 4 ml of ethanol is stirred in the presence of 6 mg of PtO2 for 12 hours under a H2 atmosphere (1 atm, 25° C.). The reaction mixture, filtered through Celite and evaporated, gave, after chromatography and sublimation, 20.5 mg of 1,2,3,4,4a,5,6,7,8,8a-decahydro-2-oxo-4a-hydroxy-5,5,8a-trimethyl-1,6-methanonaphthalene (m.p. 120°-123° C., 92% yield).

Provenance & Evidence