Nitric Acid → HCID 20541576, compound

HRID 1065182Notes

Reaction equation

HRID 1065182 reaction equation
[N+:1]([O-:4])(O)=[O:2].S(=O)(=O)(O)O.[C:10]([C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH:21]([CH3:24])[CH2:22][Cl:23])=[CH:16][CH:15]=1)([CH3:13])([CH3:12])[CH3:11]>>[C:10]([C:14]1[CH:15]=[CH:16][C:17]([CH2:20][CH:21]([CH3:24])[CH2:22][Cl:23])=[C:18]([N+:1]([O-:4])=[O:2])[CH:19]=1)([CH3:13])([CH3:11])[CH3:12]

Participants

4

Reactant 3

HCID 944Nitric AcidHCID 1118Sulfuric AcidHCID 132518171-tert-Butyl-4-(3-chloro-2-methylpropyl)benzene

Product 1

HCID 20541576HCID 20541576, compound

Procedure

440 parts by weight of nitrating acid, consisting of 200 parts by weight of concentrated nitric acid and 240 parts by weight of concentrated sulfuric acid, are added dropwise to 448 parts by weight of 3-(p-tert.-butyl-phenyl)-2-methyl-propyl chloride, whilst cooling with ice. After stirring has been continued for 3 hours at room temperature, the crude product is poured onto ice and extracted with diethyl ether, the extract is washed with water, with aqueous NaHCO3 solution and again with water and is dried over Na2SO4, the solvent is evaporated and the residue is distilled.

Workup

  1. temperaturewhilst cooling with ice
  2. extractionextracted with diethyl ether
  3. washthe extract is washed with water, with aqueous NaHCO3 solution and again with water
  4. dry with materialis dried over Na2SO4
  5. customthe solvent is evaporated
  6. distillationthe residue is distilled

Sources & evidence

ORD record
ord-7fb00f7d277d459aa945d20a46f84269
Source dataset
uspto-grants-1982_05
Patent number
US04328380

Reaction notes

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