3-Methoxybenzenethiol → 6-[4-(3-Methoxyphenyl-mercapto)-butoxy]-3,4-dihydro-carbostyril

HRID 1065323Notes

Reaction equation

Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][CH:16]=1)[NH:13][C:12](=[O:17])[CH2:11][CH2:10]2.[CH3:18][O:19][C:20]1[CH:21]=[C:22]([SH:26])[CH:23]=[CH:24][CH:25]=1>>[CH3:18][O:19][C:20]1[CH:21]=[C:22]([S:26][CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]2[CH:8]=[C:9]3[C:14](=[CH:15][CH:16]=2)[NH:13][C:12](=[O:17])[CH2:11][CH2:10]3)[CH:23]=[CH:24][CH:25]=1

Participants

Reactant 2

HCID 849893-Methoxybenzenethiol

HCID 131098086-(4-Bromobutoxy)-3,4-dihydro-carbostyril

Product 1

HCID 202606566-[4-(3-Methoxyphenyl-mercapto)-butoxy]-3,4-dihydro-carbostyril

Procedure

Prepared analogous to Example 1 from 6-(4-bromo-butoxy)-3,4-dihydro-carbostyril (m.p. 142°-147° C.) and 3-methoxy-thiophenol.

Sources & evidence

ORD record: ord-a695c732b8114d98b014acd0b34b2a1a
Source dataset: uspto-grants-1982_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04329347

Reaction notes

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