2-Furanmethanethiol → 6-[4-(2-Furylmethyl-mercapto)-butoxy]-3,4-dihydro-carbostyril

HRID 1065335Notes

Reaction equation

HRID 1065335 reaction equation
[CH2:1]([SH:7])[C:2]1[O:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:9][CH2:10][CH2:11][CH2:12][O:13][C:14]1[CH:15]=[C:16]2[C:21](=[CH:22][CH:23]=1)[NH:20][C:19](=[O:24])[CH2:18][CH2:17]2>>[O:6]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:1][S:7][CH2:9][CH2:10][CH2:11][CH2:12][O:13][C:14]1[CH:15]=[C:16]2[C:21](=[CH:22][CH:23]=1)[NH:20][C:19](=[O:24])[CH2:18][CH2:17]2

Participants

3

Reactant 2

HCID 73632-FuranmethanethiolHCID 131098086-(4-Bromobutoxy)-3,4-dihydro-carbostyril

Product 1

HCID 205400266-[4-(2-Furylmethyl-mercapto)-butoxy]-3,4-dihydro-carbostyril

Procedure

Prepared analogous to Example 1 from furfuryl-mercaptan and 6-(4-bromo-butoxy)-3,4-dihydro-carbostyril (m.p. 142°-147° C.).

Sources & evidence

ORD record
ord-f03c440055f149a69213975c6ac3d973
Source dataset
uspto-grants-1982_05
Patent number
US04329347

Reaction notes

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