2,6-Dihydroxyquinoline → 6-(4-Phenylmercapto-butoxy)-carbostyril

HRID 1065373Notes

Reaction equation

HRID 1065373 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[NH:8][C:7](=[O:12])[CH:6]=[CH:5]2.[C:13]1([S:19][CH2:20][CH2:21][CH2:22][CH2:23]Br)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[C:13]1([S:19][CH2:20][CH2:21][CH2:22][CH2:23][O:1][C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][CH:11]=2)[NH:8][C:7](=[O:12])[CH:6]=[CH:5]3)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 1770652,6-DihydroxyquinolineHCID 111841484-Phenylmercapto-butylbromide

Product 1

HCID 539993196-(4-Phenylmercapto-butoxy)-carbostyril

Procedure

Prepared analogous to Example 92 from 6-hydroxy-carbostyril and 4-phenylmercapto-butyl bromide.

Sources & evidence

ORD record
ord-206dd0393a044fb8880ba7e0c23d49a5
Source dataset
uspto-grants-1982_05
Patent number
US04329347

Reaction notes

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