2,6-Dihydroxyquinoline → 6-[4-(Benzenesulfinyl)butoxy]quinolin-2(1H)-one

HRID 1065375Notes

Reaction equation

HRID 1065375 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[NH:8][C:7](=[O:12])[CH:6]=[CH:5]2.[C:13]1([S:19]([CH2:21][CH2:22][CH2:23][CH2:24]Br)=[O:20])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[C:13]1([S:19]([CH2:21][CH2:22][CH2:23][CH2:24][O:1][C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][CH:11]=2)[NH:8][C:7](=[O:12])[CH:6]=[CH:5]3)=[O:20])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 1770652,6-DihydroxyquinolineHCID 545301224-Phenylsulfinylbutylbromide

Product 1

HCID 202606786-[4-(Benzenesulfinyl)butoxy]quinolin-2(1H)-one

Procedure

Prepared analogous to Example 92 from 6-hydroxy-carbostyril and 4-phenylsulfinyl-butyl bromide.

Sources & evidence

ORD record
ord-f57ea7d154d14a4ea930b8d519f242d8
Source dataset
uspto-grants-1982_05
Patent number
US04329347

Reaction notes

Loading…