Thiophenol → 5-(2-Hydroxy-3-phenylmercapto-propoxy)-3,4-dihydro-carbostyril

HRID 1065384Notes

Reaction equation

HRID 1065384 reaction equation
[O:1]1[CH2:16][CH:2]1[CH2:3][O:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][C:9](=[O:15])[NH:10]2.[C:17]1([SH:23])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[OH:1][CH:2]([CH2:16][S:23][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[CH2:3][O:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][C:9](=[O:15])[NH:10]2

Participants

3

Reactant 2

HCID 7969ThiophenolHCID 128994235-[(Oxiran-2-yl)methoxy]-3,4-dihydroquinolin-2(1H)-one

Product 1

HCID 536328765-(2-Hydroxy-3-phenylmercapto-propoxy)-3,4-dihydro-carbostyril

Procedure

Prepared analogous to Example 59 from 5-(2,3-epoxy-propoxy)-3,4-dihydro-carbostyril and thiophenol.

Sources & evidence

ORD record
ord-d3c0d30db3764866a84d96618d6a099b
Source dataset
uspto-grants-1982_05
Patent number
US04329347

Reaction notes

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