2,5-Dichlorobenzenethiol → HCID 20539997, compound

Participants

Reaction Steps

8.94 gm (0.03 mol) of 6-(4-bromo-butoxy)-3,4-dihydro-carbostyril (m.p. 142°-147° C.) were added to a solution of 2.21 gm (0.0315 mol) of potassium methylate and 5.76 gm (0.0315mol) of 98% 2,5-dichloro-thiophenol in 54 ml of methanol. The mixture was refluxed, whereupon at first a clear solution was obtained. After 5 minutes so much crystalline reaction product was separated out that the reaction mixture solidified into a barely stirrable crystal slurry. After one hour the mixture was cooled to room temperature, suction-filtered and the filter cake was recrystallized from ethanol. Colorless crystals with a melting point of 133°-134° C. were obtained.

Provenance & Evidence