tert-Butyl mercaptan → 5-(3-tert. Butylmercapto-2-hydroxy-propoxy)-3,4-dihydro-carbostyril

HRID 1065401Notes

Reaction equation

HRID 1065401 reaction equation
[O:1]1[CH2:16][CH:2]1[CH2:3][O:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][C:9](=[O:15])[NH:10]2.[C:17]([SH:21])([CH3:20])([CH3:19])[CH3:18]>>[C:17]([S:21][CH2:16][CH:2]([OH:1])[CH2:3][O:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][C:9](=[O:15])[NH:10]2)([CH3:20])([CH3:19])[CH3:18]

Participants

3

Reactant 2

HCID 6387tert-Butyl mercaptanHCID 128994235-[(Oxiran-2-yl)methoxy]-3,4-dihydroquinolin-2(1H)-one

Product 1

HCID 706077645-(3-tert. Butylmercapto-2-hydroxy-propoxy)-3,4-dihydro-carbostyril

Procedure

Prepared analogous to Example 133 from 5-(2,3-epoxy-propoxy)-3,4-dihydro-carbostyril (m.p. 171°-173° C.) and tert. butyl mercaptan.

Sources & evidence

ORD record
ord-5b998e00c2064c9aa87c2a15d1a3c304
Source dataset
uspto-grants-1982_05
Patent number
US04329347

Reaction notes

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