4-Methyl-6-(4-bromo-butoxy)-carbostyril → 4-Methyl-6-[4-(2-pyridyl-mercapto)-butoxy]-carbostyril

HRID 1065405Notes

Reaction equation

HRID 1065405 reaction equation
[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH2:13][CH2:14][CH2:15][CH2:16]Br)[CH:10]=2)[NH:5][C:4](=[O:18])[CH:3]=1.[SH:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=1>>[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][S:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=3)[CH:10]=2)[NH:5][C:4](=[O:18])[CH:3]=1

Participants

3

Reactant 2

HCID 205401234-Methyl-6-(4-bromo-butoxy)-carbostyrilHCID 178418616HCID 178418616, compound

Product 1

HCID 205400204-Methyl-6-[4-(2-pyridyl-mercapto)-butoxy]-carbostyril

Procedure

Prepared analogous to Example 122 from 4-methyl-6-(4-bromo-butoxy)-carbostyril (m.p. 217°-219° C.) and 2-mercapto-pyridine.

Sources & evidence

ORD record
ord-3ddb15bd3216494a8b21c100318dc5f3
Source dataset
uspto-grants-1982_05
Patent number
US04329347

Reaction notes

Loading…