6-(4-Bromobutoxy)quinolin-2(1H)-one → 6-[4-(1,2,4-Triazol-3-yl-mercapto)-butoxy]-carbostyril

HRID 1065429Notes

Reaction equation

HRID 1065429 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][CH:16]=1)[NH:13][C:12](=[O:17])[CH:11]=[CH:10]2.[SH:18][C:19]1[N:23]=[CH:22][NH:21][N:20]=1>>[NH:21]1[CH:22]=[N:23][C:19]([S:18][CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]2[CH:8]=[C:9]3[C:14](=[CH:15][CH:16]=2)[NH:13][C:12](=[O:17])[CH:11]=[CH:10]3)=[N:20]1

Participants

3

Reactant 2

HCID 152906936-(4-Bromobutoxy)quinolin-2(1H)-oneHCID 178527894HCID 178527894, compound

Product 1

HCID 1785157006-[4-(1,2,4-Triazol-3-yl-mercapto)-butoxy]-carbostyril

Procedure

Prepared analogous to Example 122 from 6-(4-bromobutoxy)-carbostyril and 3-mercapto-1,2,4-triazole.

Sources & evidence

ORD record
ord-c4eb8625858f492eba25db70fec08728
Source dataset
uspto-grants-1982_05
Patent number
US04329347

Reaction notes

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