HuagongsheHuagongshe Chemistry Print Report · For research reference only
Guaiacylacetone → HCID 20540374, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Guaiacylacetone | HCID 17262 | — |
| Reactant | 3-(Trifluoromethyl)benzyl chloride | HCID 69716 | — |
| Reactant | 3,3-Diphenylpropylamine | HCID 79698 | — |
| Product | HCID 20540374 | HCID 20540374 | — |
Reaction Steps
Reacting the (3-methoxy-4-hydroxyphenyl)-acetone with the 3,3-diphenylpropylamine, reducing the resulting Schiff's base as shown above and reacting the resulting saturated compound with 3-trifluoromethylbenzyl chloride, the 1-[3-methoxy-4-(3-trifluoromethylbenzyloxy)-phenyl]-2-(3,3-diphenylpropylamino)-propane hydrochloride is obtained, melting at 142° to 146° after recrystallization from isopropanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04329367 |
| Source dataset | uspto-grants-1982_05 |
| ORD ID | ord-3150d4a85bba4dc49a36ca04a431c3e5 |
| Source note | uspto-grants-1982_05 |