反应详情

A 10.0 g. portion of N-(dimethylaminomethylene)pyrazine carboxamide is added to a mixture of 10.3 g. of 4-nitrophenylhydrazine, 200 ml. of acetic acid and 50 ml. of p-dioxane. The mixture is heated at 90° for 5 hours and evaporated to dryness in vacuo. The residue is recrystallized from ethanol giving 9.0 g. of the desired product as tan crystals, mp. 188°-189° C.

1. temperatureThe mixture is heated at 90° for 5 hours
2. customevaporated to dryness in vacuo
3. customThe residue is recrystallized from ethanol giving 9.0 g