2-Chloro-4,5-dimethylpyrimidine → 4-[(4,5-Dimethyl-pyrimidin-2-ylamino)-methyl]-piperidine-1-carboxylic acid 4-methyl-benzyl ester

HRID 106562Notes

Reaction equation

HRID 106562 reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([CH3:9])[c:6]([CH3:8])[n:7]1.[NH2:10][CH2:11][CH:12]1[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][CH2:21][c:22]2[cH:23][cH:24][c:25]([CH3:28])[cH:26][cH:27]2)[CH2:16][CH2:17]1>>[c:2]1([NH:10][CH2:11][CH:12]2[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][CH2:21][c:22]3[cH:23][cH:24][c:25]([CH3:28])[cH:26][cH:27]3)[CH2:16][CH2:17]2)[n:3][cH:4][c:5]([CH3:9])[c:6]([CH3:8])[n:7]1

Participants

3

Reactant 2

HCID 125817842-Chloro-4,5-dimethylpyrimidineHCID 161094174-Methylbenzyl 4-(aminomethyl)1-piperidinecarboxylate

Product 1

HCID 235773034-[(4,5-Dimethyl-pyrimidin-2-ylamino)-methyl]-piperidine-1-carboxylic acid 4-methyl-benzyl ester

Sources & evidence

ORD record
ord-b1d21959d1884f48b6ef229bd04dae9c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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