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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1065635Generated: October 25, 2026

Sodium hydride → N,N-Dimethyl-3-phenyl-3-(2-pyrazinyloxy)propylamine

https://huagongshe.com/reaction/1065635

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium hydrideHCID 24758—
ReactantChloropyrazineHCID 73277—
Reactant3-(Dimethylamino)-1-phenylpropan-1-olHCID 110665—
SolventDimethyl SulfoxideHCID 679—
ProductN,N-Dimethyl-3-phenyl-3-(2-pyrazinyloxy)propylamineHCID 20539675—

Reaction Steps

Following the method of Example 3, reaction of N,N-dimethyl-3-hydroxy-3-phenylpropylamine, sodium hydride and 2-chloropyrazine in DMSO gives the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04330546
Source datasetuspto-grants-1982_05
ORD IDord-b4ab8759186d463685d80bf1bfce45dd
Source noteuspto-grants-1982_05