Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1065638Generated: October 30, 2026

Sodium hydride → N-Methyl-3-phenyl-3-(2-thienyloxy)propylamine

https://huagongshe.com/reaction/1065638

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium hydrideHCID 24758—
Reactant2-FluorothiopheneHCID 136243—
Reactant3-Methylamino-1-phenylpropanolHCID 2733989—
SolventDimethyl SulfoxideHCID 679—
ProductN-Methyl-3-phenyl-3-(2-thienyloxy)propylamineHCID 20539676—

Reaction Steps

Following the method of Example 4, reaction of 3-hydroxy-N-methyl-3-phenylpropylamine, sodium hydride and 2-fluorothiophen in DMSO gives the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04330546
Source datasetuspto-grants-1982_05
ORD IDord-8dfbbc3129c044f7a3af79c5b24dbea7
Source noteuspto-grants-1982_05