Hydrogen Bromide → HCID 20539725, compound

Participants

Reaction Steps

A mixture of 800 ml of glacial acetic acid and 80 ml of 63 percent hydrobromic acid is poured over 37.4 g (0.1 mole) of N-ethyoxycarbonylheptyl-2-oxo-5-phenyl-4-oxazolin-3-ylcarboxamide and the mixture is heated under reflux for 2 hours and evaporated as completely as possible in vacuo. The residue is stirred with water. The crude product which is precipitated is separated and washed with a little water. After drying, the compound is purified by column chromatography (silica gel//CHCl3 /methanol).

Provenance & Evidence