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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1065666Generated: October 25, 2026

4-oxo-L-proline → 1-[3-[[(4-methoxy)phenylmethyl]thio]-2-trifluoromethyl-1-oxopropyl]-4-oxo-L-proline

https://huagongshe.com/reaction/1065666

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-oxo-L-prolineHCID 107541—
Reactant3-[[(4-Methoxy)phenylmethyl]thio]-2-trifluoromethylpropionyl chlorideHCID 12941229—
Product1-[3-[[(4-methoxy)phenylmethyl]thio]-2-trifluoromethyl-1-oxopropyl]-4-oxo-L-prolineHCID 22817840—

Reaction Steps

The 3-[[(4-methoxy)phenylmethyl]thio]-2-trifluoromethylpropionyl chloride from part (a) is reacted with 4-keto-L-proline to yield 1-[3-[[(4-methoxy)phenylmethyl]thio]-2-trifluoromethyl-1-oxopropyl]-4-oxo-L-proline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04330548
Source datasetuspto-grants-1982_05
ORD IDord-4a3f2f29405d4b099b5938e034f8a7eb
Source noteuspto-grants-1982_05