Hydrochloric Acid → HCID 12961947, compound

Participants

Reaction Steps

A cold (0° C.) solution of hydrogen chloride (2 g) in methanol (10 ml) was added with stirring to a solution of 17β-methylamino-5α-androstane-3β,16α-diol 3-acetate (16 g) in methanol (16 ml) and chloroform (48 ml) at 0° C. Ether (300 ml) was added to precipitate 17β-methylamino-5α-androstane-3β,16α-diol 3-acetate hydrochloride as prisms (16 g), m.p. >270° C. (decomp.), [α]D +113° (C 1.04 in MeOH).

Provenance & Evidence