Acetone → HCID 12961967, compound

Participants

Reaction Steps

Hydrogen chloride gas has passed through a solution of 5α,6β-dichloro-17β-methylamino-5α-androstane-3β,16α-diol (7.2 g) in methanol (15 ml) and chloroform (72 ml), giving a colourless precipitate. Evaporation of the solvent gave a colourless residue which was heated with acetone, filtered, and dried in vacuo to give 5α,6β-dichloro-17β-methylamino-5α-androstane-3β,16α-diol hydrochloride as prisms (7.5 g), m.p.>210° C. (decomp.), [α]D -57.1° (c 1.1 in EtOH).

Provenance & Evidence