HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylamine → HCID 12962025, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | Maleic Acid | HCID 444266 | — |
| Reactant | Potassium Bicarbonate | HCID 516893 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 86738380 | HCID 86738380 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 12962025 | HCID 12962025 | — |
Reaction Steps
In a similar way as described in Example XXI 3,16α-dihydroxy-oestra-1,3,5(10)-trien-17-one diacetate was converted with ethylamine into the intermediate 17-ethylimine, which was reduced with sodium borohydride. Hydrolysis with potassium bicarbonate, followed by treatment with maleic acid gave the title compound, m.p. 147° C. (decomp.), [α]D +32.9° (c 1.07 in dimethylsulphoxide).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04330539 |
| Source dataset | uspto-grants-1982_05 |
| ORD ID | ord-5ae8baa4dcda4f4a9b91b561a3ed1ab8 |
| Source note | uspto-grants-1982_05 |