Potassium Hydroxide → N-(3,5-dichloro-4,6-dimethyl-2-pyridyl)-2,4-dinitro-6-trifluoromethylaniline

Participants

Reaction Steps

In 20 ml. of dimethylformamide, 1.9 g. of 2-amino-3,5-dichloro-4,6-dimethylpyridine was dissolved and 0.7 g. of powdery potassium hydroxide was gradually added with stirring and a solution of 2.7 g. of 2,4-dinitro-6-trifluoromethylchlorobenzene in 10 ml. of dimethylformamide was added dropwise at room temperature to react them for about 10 hours. The reaction mixture was treated as the process of Preparation No. 7 to obtain 1.6 g. of the object compound having the melting point of 131° to 133° C.

Provenance & Evidence