Acetic Acid → HCID 54267703, compound

Participants

Reaction Steps

16.7 g (0.1 mole) of pinacolyl-1,2,4-triazole, 15.6 g (0.1 mole) of 2-naphthaldehyde, 1 g of piperidine and 3 g of glacial acetic acid in 50 ml of toluene were heated under reflux, using a water separator, until no further water passed over. After cooling the reaction solution, it was diluted by adding ether and washed with water. The organic phase was dried over sodium sulphate and concentrated by distilling off the solvents in vacuo. The residue was distilled in vacuo. 18 g (59% of theory) of 4,4-dimethyl-1-(naphth-2-yl)-2-(1,2,4-triazol-1-yl)-1-penten-3-one of boiling point 220° C. were obtained.

Provenance & Evidence