Methanethiol → HCID 178503166, compound

Participants

Reaction Steps

Hydrazine hydrate (4 g, 3.9 ml) was added dropwise to a cooled solution of the product of Example 1 (15 g) in ethanol (75 ml). The reaction mixture was refluxed until evolution of methyl mercaptan ceased (2 hours), and allowed to cool. Most of the ethanol was evaporated off, and the residue was pitched into water, and ether extracted. The ethereal solution was dried over magnesium sulphate, and evaporated to give a pale yellow solid, which was recrystallised from 1:1 benzene/60°-80° petrol to give 3-t-butyl-5-(methylthio)pyrazole, 6.0 g, (48% yield), melting point 142°-4°.

Provenance & Evidence