O-Allylhydroxylamine hydrochloride → 2-Allyloxyimino-2-(3-chloro-4-hydroxyphenyl)acetic acid

HRID 1065878Notes

Reaction equation

HRID 1065878 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9](=O)[C:10]([OH:12])=[O:11])[CH:5]=[CH:6][C:7]=1[OH:8].Cl.[CH2:15]([O:18][NH2:19])[CH:16]=[CH2:17]>>[CH2:15]([O:18][N:19]=[C:9]([C:4]1[CH:5]=[CH:6][C:7]([OH:8])=[C:2]([Cl:1])[CH:3]=1)[C:10]([OH:12])=[O:11])[CH:16]=[CH2:17]

Participants

3

Reactant 2

HCID 3084724O-Allylhydroxylamine hydrochlorideHCID 129611392-(3-Chloro-4-hydroxyphenyl)-2-oxoacetic acid

Product 1

HCID 1362107842-Allyloxyimino-2-(3-chloro-4-hydroxyphenyl)acetic acidYield 98.1%

Procedure

2-(3-Chloro-4-hydroxyphenyl)glyoxylic acid (2 g.) and O-allylhydroxylamine hydrochloride (1.1 g.) were reacted according to a similar manner to that of Preparation (5-2)(a) to give oil of 2-allyloxyimino-2-(3-chloro-4-hydroxyphenyl)acetic acid (syn isomer) (2.5 g.).

Sources & evidence

ORD record
ord-90034140103b470fb79a9f1b5f2fdd0d
Source dataset
uspto-grants-1982_05
Patent number
US04331664

Reaction notes

Loading…