HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 106598Generated: October 29, 2026
1-(2-Hydroxyethyl)piperazine → 1-(5-Tert-butylisoxazol-3-yl)-3-(3-(7-(2-(4-(2-hydroxyethyl)piperazin-1-yl)ethoxy)-6-methoxyquinazolin-4-ylthio)phenyl)urea
https://huagongshe.com/reaction/106598
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-(2-Hydroxyethyl)piperazine | HCID 7677 | — |
| Reactant | Tetrabutylammonium | HCID 16028 | — |
| Reactant | Iodide Ion | HCID 30165 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 1-(5-tert-Butyl-isoxazol-3-yl)-3-{3-[7-(2-chloro-ethoxy)-6-methoxy-quinazolin-4-ylsulfanyl]-phenyl}-urea | HCID 66876047 | — |
| Product | 1-(5-Tert-butylisoxazol-3-yl)-3-(3-(7-(2-(4-(2-hydroxyethyl)piperazin-1-yl)ethoxy)-6-methoxyquinazolin-4-ylthio)phenyl)urea | HCID 58267833 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (2/10) |
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| ORD ID | ord-15a89eab7a4f40b790aa2abcf08e9ae3 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (2/10) |
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