HCID 10583869, compound → HCID 10687511, compound

Participants

Reaction Steps

Following the same procedure as in example 1 step F, but using 4(S)-benzyl-3(S)-methoxyazetidin-2-one as starting material and 4-{{(phenoxycarbonyl)amino}methyl}pyridine as reactant, 4(S)-benzyl-3(S)-methoxy-2-oxoazetidine-1-carboxylic acid (4-pyridinylmethyl)amide was obtained as a light yellow oil. 1H-NMR (400 MHz, CDCl3) δ8.60-7.22 (m, 9H), 7.06-7.04 (m, 1H), 4.52-4.50 (m, 2H), 4.28 (d, J=2.2 Hz, 1H), 4.21-4.17 (m, 1H), 3.57 (dd, J=14, 3.5 Hz, 1H), 3.15 (s, 3H), 2.93 (dd, J=14.2, 8.9 Hz, 1H); IR (neat) υ1773,1770 cm−1; FAB-MS m/z 329 (MH+); HRMS calcd for C18H20N3O3: 326.1504 (MH+); found: 326.1519.

Provenance & Evidence