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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1066080Generated: October 26, 2026

3-Chloropropyl 3,4-dimethylphenyl ether → 1-(3-(3,4-Dimethylphenoxy)prop-1-yl)-4-hydroxy-4-(quinolin-3-yl)piperidine

https://huagongshe.com/reaction/1066080

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloropropyl 3,4-dimethylphenyl etherHCID 16788005—
Reactant4-(Quinolin-3-yl)piperidin-4-olHCID 21198010—
Product1-(3-(3,4-Dimethylphenoxy)prop-1-yl)-4-hydroxy-4-(quinolin-3-yl)piperidineHCID 986521127%

Reaction Steps

Beginning with 0.218 gm (1.1 mMol) 3-chloropropyl 3,4-dimethylphenyl ether and 0.250 gm (1.1 mMol) 4-hydroxy-4-(quinolin-3-yl)piperidine, 0.114 gm (27%) of the title compound were recovered as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06242450B1
Source datasetuspto-grants-2001_06
ORD IDord-ce9548cf8a4340fa89ca0a3aaca6aeeb
Source noteuspto-grants-2001_06