HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-chloropropoxy)-1H-indole → 1-(3-(Indol-4-yloxy)prop-1-yl)-4-hydroxy-4-(isoquinolin-4-yl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-chloropropoxy)-1H-indole | HCID 11694169 | — |
| Reactant | HCID 21198018 | HCID 21198018 | — |
| Product | 1-(3-(Indol-4-yloxy)prop-1-yl)-4-hydroxy-4-(isoquinolin-4-yl)piperidine | HCID 15523993 | 48% |
Reaction Steps
Beginning with 0.184 gm (0.88 mMol) 3-chloropropyl indol-4-yl ether and 0.200 gm (0.88 mMol) 4-hydroxy-4-(isoquinolin-4-yl)piperidine, 0.169 gm (48%) of the title compound were recovered as a light yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06242450B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-386266836b1d4d4da09d215a34adbdb0 |
| Source note | uspto-grants-2001_06 |