HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(3-Chloro-propoxy)-1H-indole → 1-(3-(Indol-5-yloxy)prop-1-yl)-4-hydroxy-4-(quinolin-3-yl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(3-Chloro-propoxy)-1H-indole | HCID 11499455 | — |
| Reactant | 4-(Quinolin-3-yl)piperidin-4-ol | HCID 21198010 | — |
| Product | 1-(3-(Indol-5-yloxy)prop-1-yl)-4-hydroxy-4-(quinolin-3-yl)piperidine | HCID 9909035 | 45.6% |
Reaction Steps
Beginning with 0.275 gm (1.3 mMol) 3-chloropropyl indol-5-yl ether and 0.300 gm (1.3 mMol) 4-hydroxy-4-(quinolin-3-yl)piperidine, 0.238 gm (45%) of the title compound were recovered as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06242450B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-ff839a0ac182457f900dabe568b32228 |
| Source note | uspto-grants-2001_06 |