反应详情

Starting from 2-amino-4-hexylbenzenesulfonamide and isopropyl isothiocyanate, and following a procedure analogous to the one described in Example 4a, N-(2-amino-4-hexylbenzenesulfonyl)-N′-isopropylthiourea was prepared. The crude product was obtained as an oil and used without purification. Subsequent ring closure with phosgene by a procedure analogous to the one described in Example 4b gave the title compound; m.p. 319-321° C.

1. customwas prepared
2. customThe crude product was obtained as an oil
3. customused without purification