Sec-Butylamine → HCID 178448908, compound
Reaction equation
N1([C:6]2[NH:11][C:10]3[CH:12]=[CH:13][C:14]([C:16]([F:19])([F:18])[F:17])=[CH:15][C:9]=3[S:8](=[O:21])(=[O:20])[N:7]=2)C=CN=C1.[CH:22]([NH2:26])([CH2:24][CH3:25])[CH3:23]>>[CH:22]([NH:26][C:6]1[NH:11][C:10]2[CH:12]=[CH:13][C:14]([C:16]([F:18])([F:17])[F:19])=[CH:15][C:9]=2[S:8](=[O:21])(=[O:20])[N:7]=1)([CH2:24][CH3:25])[CH3:23]Participants
3
Procedure
3-(Imidazol-1-yl)-7-trifluoromethyl-4H-1,2,4-benzothiadiazine 1,1-dioxide was treated with sec-butylamine according to the general procedure Method A to give the title compound; m.p. 234-236° C.
Sources & evidence
- ORD record
- ord-27288367da3b4eeabefb4e21ed55553c
- Source dataset
- uspto-grants-2001_06
- Patent number
- US06242443B1
Reaction notes
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