Cyclopropanemethanamine → HCID 178527185, compound
Reaction equation
[N:1]1([C:6]2[NH:11][C:10]3[CH:12]=[CH:13][C:14]([C:16]([F:19])([F:18])[F:17])=[CH:15][C:9]=3[S:8](=[O:21])(=[O:20])[N:7]=2)[CH:5]=[CH:4]N=C1.[CH:22]1(CN)C[CH2:23]1>>[CH:4]1([CH2:5][NH:1][C:6]2[NH:11][C:10]3[CH:12]=[CH:13][C:14]([C:16]([F:17])([F:19])[F:18])=[CH:15][C:9]=3[S:8](=[O:20])(=[O:21])[N:7]=2)[CH2:23][CH2:22]1Participants
3
Procedure
3-(Imidazol-1-yl)-7-trifluoromethyl-4H-1,2,4-benzothiadiazine 1,1-dioxide was treated with cyclopropylmethylamine according to the general procedure Method D to give the title compound; m.p. 266-268° C.
Sources & evidence
- ORD record
- ord-f4f4de355ce04844828776d60e348d09
- Source dataset
- uspto-grants-2001_06
- Patent number
- US06242443B1
Reaction notes
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