5-Methoxy-o-toluidine → N-(5-Methoxy-2-methylphenyl)-tricyclo[3.3.1.13,7]decane-1-acetamide

HRID 1066235Notes

Reaction equation

HRID 1066235 reaction equation
[C:1]12([CH2:11][C:12](Cl)=[O:13])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[CH3:15][O:16][C:17]1[CH:18]=[CH:19][C:20]([CH3:24])=[C:21]([CH:23]=1)[NH2:22]>>[CH3:15][O:16][C:17]1[CH:18]=[CH:19][C:20]([CH3:24])=[C:21]([NH:22][C:12](=[O:13])[CH2:11][C:1]23[CH2:10][CH:5]4[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]4)[CH2:2]2)[CH2:8]3)[CH:23]=1

Participants

3

Reactant 2

HCID 995005-Methoxy-o-toluidineHCID 27718821-Adamantaneacetyl chloride

Product 1

HCID 9926842N-(5-Methoxy-2-methylphenyl)-tricyclo[3.3.1.13,7]decane-1-acetamideYield 14.6%

Procedure

Prepared according to the method of Example 1b) from 1-adamantaneacetyl chloride (0.2 g) and 5-methoxy-2-methylaniline (0.13 g) to give the title compound as a white solid (0.043 g).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-1b756a827680434285d74c58ce021a44
Source dataset
uspto-grants-2001_06
Patent number
US06242470B1

Reaction notes

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