1-Adamantaneacetyl chloride → HCID 20660003, compound

HRID 1066242Notes

Reaction equation

HRID 1066242 reaction equation
[C:1]12([CH2:11][C:12](Cl)=[O:13])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.Cl.[NH2:16][C:17]1[CH:25]=[CH:24][CH:23]=[C:22]2[C:18]=1[CH:19]=[CH:20][NH:21]2>>[NH:21]1[C:22]2[C:18](=[C:17]([NH:16][C:12](=[O:13])[CH2:11][C:1]34[CH2:10][CH:5]5[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]5)[CH2:2]3)[CH2:8]4)[CH:25]=[CH:24][CH:23]=2)[CH:19]=[CH:20]1

Participants

3

Reactant 2

HCID 27718821-Adamantaneacetyl chlorideHCID 224615721H-Indol-4-amine--hydrogen chloride (1/1)

Product 1

HCID 20660003HCID 20660003, compoundYield 63.4%

Procedure

Prepared according to the method of Example 1b) from 1-adamantaneacetyl chloride (0.074 g) and 4-aminoindole hydrochloride (0.059 g) to give the title compound as a white solid (0.068 g).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e31a533a006a4ee592d2f21134fd80a9
Source dataset
uspto-grants-2001_06
Patent number
US06242470B1

Reaction notes

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