5-Nitroindole → HCID 21198563, compound

HRID 1066245Notes

Reaction equation

HRID 1066245 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[NH:9][CH:8]=[CH:7]2)([O-:3])=[O:2].Cl.[CH3:14][N:15]([CH2:17][CH2:18]Cl)[CH3:16]>>[CH3:14][N:15]([CH:17]([N:9]1[C:10]2[C:6](=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:12][CH:11]=2)[CH:7]=[CH:8]1)[CH3:18])[CH3:16]

Participants

3

Reactant 2

HCID 225235-NitroindoleHCID 11636816N,N-Dimethylaminoethyl chloride hydrochloride

Product 1

HCID 21198563HCID 21198563, compoundYield 76.9%

Procedure

Prepared according to the method of Example 15a) from 5-nitroindole (0.217 g) and dimethylaminoethyl chloride hydrochloride (0.21 g) to leave sub-title compound as an orange/brown solid (0.24 g).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a831a53bd2994ea09557577a11c451eb
Source dataset
uspto-grants-2001_06
Patent number
US06242470B1

Reaction notes

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