2-Methyl-4-methoxyaniline → HCID 20660022, compound

HRID 1066248Notes

Reaction equation

HRID 1066248 reaction equation
[C:1]12([CH2:11][C:12](Cl)=[O:13])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[CH3:15][O:16][C:17]1[CH:23]=[CH:22][C:20]([NH2:21])=[C:19]([CH3:24])[CH:18]=1>>[CH3:15][O:16][C:17]1[CH:23]=[CH:22][C:20]([NH:21][C:12](=[O:13])[CH2:11][C:1]23[CH2:10][CH:5]4[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]4)[CH2:2]2)[CH2:8]3)=[C:19]([CH3:24])[CH:18]=1

Participants

3

Reactant 2

HCID 76102-Methyl-4-methoxyanilineHCID 27718821-Adamantaneacetyl chloride

Product 1

HCID 20660022HCID 20660022, compoundYield 46.5%

Procedure

Prepared according to the method of Example 1b) from 1-adamantaneacetyl chloride (2.0 g) and 4-methoxy-2-methylaniline (1.29 g) to give the title compound as a white solid (1.37 g).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-1b4c38f9ccb846ea94924ca6b367e47d
Source dataset
uspto-grants-2001_06
Patent number
US06242470B1

Reaction notes

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