HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Amino-4-methylphenyl)methanol → N-(5-Hydroxymethyl-2-methylphenyl)-tricyclo[3.3.1.13,7]decane-1-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Amino-4-methylphenyl)methanol | HCID 586243 | — |
| Reactant | 1-Adamantaneacetyl chloride | HCID 2771882 | — |
| Product | N-(5-Hydroxymethyl-2-methylphenyl)-tricyclo[3.3.1.13,7]decane-1-acetamide | HCID 20660024 | 37.3% |
Reaction Steps
Prepared according to the method of Example 1b) from 1-adamantaneacetyl chloride (2.0 g) and 3-amino4-methylbenzyl alcohol (1.29 g). Silica gel chromatography, eluting with 5% ethylacetate in dichloromethane gave the title compound as a white solid (1.10 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06242470B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-f25aab50032645d3957dc2962eedf142 |
| Source note | uspto-grants-2001_06 |