2-Amino-o-cresol → N-(3-Hydroxy-2-methylphenyl)-tricyclo[3.3.1.13,7]decane-1-acetamide

HRID 1066252Notes

Reaction equation

HRID 1066252 reaction equation
[C:1]12([CH2:11][C:12](Cl)=[O:13])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[NH2:15][C:16]1[C:17]([CH3:23])=[C:18]([OH:22])[CH:19]=[CH:20][CH:21]=1>>[OH:22][C:18]1[C:17]([CH3:23])=[C:16]([NH:15][C:12](=[O:13])[CH2:11][C:1]23[CH2:10][CH:5]4[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]4)[CH2:2]2)[CH2:8]3)[CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 1044482-Amino-o-cresolHCID 27718821-Adamantaneacetyl chloride

Product 1

HCID 20660018N-(3-Hydroxy-2-methylphenyl)-tricyclo[3.3.1.13,7]decane-1-acetamide

Procedure

Prepared according to the method of Example 1b) from 1-adamantaneacetyl chloride (0.81) and 3-amino-2-methylphenol (0.5 g) to give the title compound as a white solid (0.5 g).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-3de98bee4de042ebba7c143cb4cd5cae
Source dataset
uspto-grants-2001_06
Patent number
US06242470B1

Reaction notes

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