4-Amino-3-chlorophenol → N-(2-Chloro-4-hydroxyphenyl)-tricyclo[3.3.1.13,7]decane-1-acetamide

HRID 1066253Notes

Reaction equation

HRID 1066253 reaction equation
[C:1]12([CH2:11][C:12](Cl)=[O:13])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[Cl:15][C:16]1[CH:22]=[C:21]([OH:23])[CH:20]=[CH:19][C:17]=1[NH2:18]>>[Cl:15][C:16]1[CH:22]=[C:21]([OH:23])[CH:20]=[CH:19][C:17]=1[NH:18][C:12](=[O:13])[CH2:11][C:1]12[CH2:2][CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:9]3)[CH2:8]1)[CH2:10]2

Participants

3

Reactant 2

HCID 871844-Amino-3-chlorophenolHCID 27718821-Adamantaneacetyl chloride

Product 1

HCID 20660004N-(2-Chloro-4-hydroxyphenyl)-tricyclo[3.3.1.13,7]decane-1-acetamide

Procedure

Prepared according to the method of Example 1b) from 1-adamantaneacetyl chloride (2.9 g) and 2-chloro-4-hydroxyaniline to give the title compound as a white solid. (0.15 g).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-f1175f4864a14a0b91e60a056302ba28
Source dataset
uspto-grants-2001_06
Patent number
US06242470B1

Reaction notes

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