HCID 20660016, compound → HCID 20660014, compound

Participants

Reaction Steps

A solution of dimethoxy ether from Example 43 (2.0 g) in 50% hycdrobromic acid in acetic acid was heated at 100 degrees for 12 hours. The solution was concentrated under vacuum, the residue taken in water and extracted with ethyl acetate. The organic layers were dried over magnesium sulfate, filtered, concentrated under vacuum. The crude material was purified over silica eluting with dichloromethane' ethyl acetateto afford the title compound as a white solid.

Provenance & Evidence