Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | HCID 131722601 | HCID 131722601 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 59910718 | HCID 59910718 | 66% |
Reaction Steps
The compound (5-a)(0.311 g) was dissolved in the solvent mixture (acetic acid:THF:water=2:1:1)(5 ml) and the solution was maintained at 50° C. for 3 hours. The crude product obtained by the conventional treatment of the reaction mixture was purified on silica gel column to give the titled compound (6-a)[yield:0.156 g (66%)].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06242485B1 |
|---|
| Source dataset | uspto-grants-2001_06 |
|---|
| ORD ID | ord-fc8f68bf10a74fc58e3bbb7cd6b75145 |
|---|
| Source note | uspto-grants-2001_06 |
|---|
